Transient growth in Taylor-Couette flow

Transient growth due to non-normality is investigated for the Taylor-Couette problem with counter-rotating cylinders as a function of aspect ratio eta and Reynolds number Re. For all Re < 500, transient growth is enhanced by curvature, i.e. is greater for eta < 1 than for eta = 1, the plane Couette limit. For fixed Re < 130 it is found that the greatest transient growth is achieved for eta between the Taylor-Couette linear stability boundary, if it exists, and one, while for Re > 130 the greatest transient growth is achieved for eta on the linear stability boundary. Transient growth is shown to be approximately 20% higher near the linear stability boundary at Re = 310, eta = 0.986 than at Re = 310, eta = 1, near the threshold observed for transition in plane Couette flow. The energy in the optimal inputs is primarily meridional; that in the optimal outputs is primarily azimuthal. Pseudospectra are calculated for two contrasting cases. For large curvature, eta = 0.5, the pseudospectra adhere more closely to the spectrum than in a narrow gap case, eta = 0.99

The CNGS Neutrino Beam

The CERN to Gran Sasso Neutrino beam (CNGS) was commissioned at CERN in early August 2006 and was first sent at low intensity to Gran Sasso on August 17, 2006. The Borexino, LVD and OPERA experiments continued the commissioning of their detectors and started taking data with practically no dead time. The CNGS collected several hundred events with clean time distributions.Comment: 11 pages, 14 EPS figures. Lecture given at the 2nd Latin American School on Cosmic Rays and Astrophysics, Puebla, Mexico, 30th August - 8th September 200

Pedagogical interaction during problem modeling

Some features of pedagogical interaction in terms of problem modeling are discussed in this article, the concept of problem modeling as an innovative approach in education is givenВ статье раскрыты некоторые особенности педагогического взаимодействия в условиях проблемного моделирования, дано понятие проблемного моделирования как инновационного подхода в образовани

Urban beaches are environmental hotspots for antibiotic resistance following rainfall

© 2019 Elsevier Ltd To reveal the occurrence and mechanisms for dispersal of antibiotic resistance (AbR) among the microbial assemblages inhabiting impacted coastal environments, we performed a weekly, two-year duration time-series study at two urban beaches between 2014 and 2016. We combined quantitative PCR and multiplex PCR/reverse line blot techniques to track patterns in the occurrence of 31 AbR genes, including genes that confer resistance to antibiotics that are critically important antimicrobials for human medicine. Patterns in the abundance of these genes were linked to specific microbial groups and environmental parameters by coupling qPCR and 16S rRNA amplicon sequencing data with network analysis. Up to 100-fold increases in the abundance of several AbR genes, including genes conferring resistance to quinolones, trimethoprim, sulfonamides, tetracycline, vancomycin and carbapenems, occurred following storm-water and modelled wet-weather sewer overflow events. The abundance of AbR genes strongly and significantly correlated with several potentially pathogenic bacterial OTUs regularly associated with wastewater infrastructure, such as Arcobacter, Acinetobacter, Aeromonas and Cloacibacterium. These high-resolution observations provide clear links between storm-water discharge and sewer overflow events and the occurrence of AbR in the coastal microbial assemblages inhabiting urban beaches, highlighting a direct mechanism for potentially significant AbR exposure risks to humans

Determining Neutrino Mass Hierarchy by Precision Measurements in Electron and Muon Neutrino Disappearance Experiments

Recently a new method for determining the neutrino mass hierarchy by comparing the effective values of the atmospheric \Delta m^2 measured in the electron neutrino disappearance channel, \Delta m^2(ee), with the one measured in the muon neutrino disappearance channel, \Delta m^2(\mu \mu), was proposed. If \Delta m^2(ee) is larger (smaller) than \Delta m^2(\mu \mu) the hierarchy is of the normal (inverted) type. We re-examine this proposition in the light of two very high precision measurements: \Delta m^2(\mu \mu) that may be accomplished by the phase II of the Tokai-to-Kamioka (T2K) experiment, for example, and \Delta m^2(ee) that can be envisaged using the novel Mossbauer enhanced resonant \bar\nu_e absorption technique. Under optimistic assumptions for the systematic uncertainties of both measurements, we estimate the parameter region of (\theta_13, \delta) in which the mass hierarchy can be determined. If \theta_13 is relatively large, sin^2 2\theta_13 \gsim 0.05, and both of \Delta m^2(ee) and \Delta m^2(\mu \mu) can be measured with the precision of \sim 0.5 % it is possible to determine the neutrino mass hierarchy at > 95% CL for 0.3 \pi \lsim \delta \lsim 1.7 \pi for the current best fit values of all the other oscillation parameters.Comment: 12 pages, 6 postscript figure

Performance of Hamamatsu 64-anode photomultipliers for use with wavelength--shifting optical fibres

Hamamatsu R5900-00-M64 and R7600-00-M64 photomultiplier tubes will be used with wavelength--shifting optical fibres to read out scintillator strips in the MINOS near detector. We report on measurements of the gain, efficiency, linearity, crosstalk, and dark noise of 232 of these PMTs, of which 219 met MINOS requirements.Comment: 15 pages, 12 figures. Accepted by Nucl. Inst. Meth.

Probing long-range leptonic forces with solar and reactor neutrinos

In this work we study the phenomenological consequences of the existence of long-range forces coupled to lepton flavour numbers in solar neutrino oscillations. We study electronic forces mediated by scalar, vector or tensor neutral bosons and analyze their effect on the propagation of solar neutrinos as a function of the force strength and range. Under the assumption of one mass scale dominance, we perform a global analysis of solar and KamLAND neutrino data which depends on the two standard oscillation parameters, \Delta m^2_{21} and \tan^2\theta_{12}, the force coupling constant, its range and, for the case of scalar-mediated interactions, on the neutrino mass scale as well. We find that, generically, the inclusion of the new interaction does not lead to a very statistically significant improvement on the description of the data in the most favored MSW LMA (or LMA-I) region. It does, however, substantially improve the fit in the high-\Delta m^2 LMA (or LMA-II) region which can be allowed for vector and scalar lepto-forces (in this last case if neutrinos are very hierarchical) at 2.5\sigma. Conversely, the analysis allows us to place stringent constraints on the strength versus range of the leptonic interaction.Comment: 20 pages, 8 figure

Transition from the Couette-Taylor system to the plane Couette system

We discuss the flow between concentric rotating cylinders in the limit of large radii where the system approaches plane Couette flow. We discuss how in this limit the linear instability that leads to the formation of Taylor vortices is lost and how the character of the transition approaches that of planar shear flows. In particular, a parameter regime is identified where fractal distributions of life times and spatiotemporal intermittency occur. Experiments in this regime should allow to study the characteristics of shear flow turbulence in a closed flow geometry.Comment: 5 pages, 5 figure

Inhibition of Vaginal Lactobacilli by a Bacteriocin-Like Inhibitor Produced by Enterococcus faecium 62-6: Potential Significance for Bacterial Vaginosis

Objective: Bacterial vaginosis (BV) is characterized by a shift in vaginal tract ecology, which includes a decrease in the concentration and/or prevalence of facultative lactobacilli. Currently, mechanisms which could account for the disappearance of lactobacilli are not well understood. The objective of this study was to determine whether vaginal streptococci/enterococci can produce bacteriocin-like inhibitors antagonistic to vaginal lactobacilli. Methods: Seventy strains of vaginal streptococci or enterococci were tested for antagonistic activities against vaginal lactobacilli using the deferred antagonism technique. Results: One strain, Enterococcus faecium 62-6, which strongly inhibited growth of lactobacilli was selected for further characterization. The spectrum of inhibitory activity of strain 62-6 included Gram-positive organisms from the vaginal environment, although native lactobacilli from the same host were resistant to inhibitor action. Following growth inMRSbroth the strain 62-6 inhibitor was shown to be heat- (100℃, 30 minutes), cold- (4℃, less than 114 days) and pH- (4–7) stable. The sensitivity of inhibitor-containing supernatants to pepsin and α-chymotrypsin suggested an essential proteinaceous component. The inhibitor was sensitive to lipase but resistant to lysozyme. Dialysis of inhibitor-containing culture supernatants suggested a molecular mass greater than 12 000 Da. All physicochemical properties were consistent with its classification as a bacteriocin-like inhibitor. Kinetic assays demonstrated a sharp onset of inhibitor production coinciding with a concentration of 62-6 of 10(7) cfu/ml, suggesting that production may be regulated by quorum sensing. Conclusions: These results may have clinical significance as a novel mechanism to account for the decline of vaginal Lactobacillus populations and contribute to both the establishment and recurrence of BV